Aciloc 300 Mg

Last Updated on 04/27/2026 ✔ Medically Reviewed by Dr. Arjun Srivastav

What Is Aciloc 300 Mg?

Aciloc 300 mg contains ranitidine (300 mg) and is used to reduce excess stomach acid. It belongs to a class of medicines called H2 blockers, which help relieve acid-related problems.

Aciloc 300 mg is a medicine that helps with problems caused by too much stomach acid. You get 300 mg of Ranitidine as the generic element in each Aciloc 300 mg.

The doctors recommend it for conditions such as-

• GERD, which helps to reduce heartburn and stomach acids
• Erosive esophagitis, which reduces the inflammation along the food pipe
• Stomach and duodenal ulcers
• Gastric ulcers due to the use of NSAIDs for a long time

Ranitidine and other H2 blocker histamine antagonists are better than the old proton pump inhibitors, like omeprazole, giving faster action. However, in some parts of Australia, the drug has been withdrawn from safe status because of its carcinogenic concerns.

✓ Composition:

• Active Ingredient: Ranitidine is the chief generic element inside the medicine in a tablet of Aciloc 300 mg.
• Appearance: Rounded film-coated tablet, pale yellow or off-white in colour.

✓ Manufacturer:

Cadila Pharmaceuticals Ltd is the manufacturer of the Aciloc 300 mg pills.

✓ Onset Of Action:

• Peak Plasma Concentration: Ranitidine reaches its peak levels in your blood within 1 to 2 hours of intake.
• Beginning of changes: It usually acts fast and clears symptoms of heartburn, stomach cramps, and pain or irritation within 2 hours of intake.

Aciloc 300 Uses

Aciloc 300 mg (ranitidine) was used to reduce stomach acid and manage several acid-related conditions.

✓ Heartburn & Acid Indigestion

• Relieves burning sensation in the chest
• Controls excess stomach acid

✓ Acid Reflux (GERD)

• Treats Gastroesophageal Reflux Disease
• Prevents acid from flowing back into the food pipe

✓ Stomach & Intestinal Ulcers

• Used for Peptic Ulcer Disease
• Helps ulcers heal faster by lowering acid levels

✓ High Acid Production Disorders

• Conditions like Zollinger–Ellison syndrome
• Controls excessive acid secretion

✓ Ulcer Prevention

• May be used to prevent ulcers caused by painkillers (NSAIDs)

Mechanism Of Action:

✓ Stopping Histamine:

The stomach has receptors called histamine H2 receptors on the cells that make acid.

✓ Stopping Acid Release:

Ranitidine sticks to these H2 receptors, which stops histamine from working.

✓ Reducing Volume and Concentration:

The medicine reduces the volume of juice and the acid level in it by stopping a certain signal.

This signal is what makes the stomach produce a lot of juice with high acid levels. So, when the medicine inhibits this signal, it reduces both the volume of juice and its acid level.

✓ Promoting symptom healing:

When the acid level is lower, the stomach and the food pipe,

also known as the oesophagus, are not irritated much. This allows the damaged tissues and ulcers in the stomach and the oesophagus to heal on their own naturally.

How Long Does It Last?

Aciloc 300 mg (ranitidine) was known for providing moderate, long-lasting acid control, but not as long as newer medicines like PPIs.

✓ Duration of Action

• Starts working within 1–3 hours
• Effects last for about 10–12 hours
• Often taken once or twice daily, depending on the condition

✓ Relief Timeline

• Heartburn relief: within a few hours
• Acid reflux control: improves over a few days
• Ulcer healing: may take weeks of regular use

Benefits Of Aciloc 300 Mg:

1. Faster Symptom Relief

The main advantage of this medicine is that it works fast. It does not need any stomach acid to start working. It begins to reduce acid in about 2 to 3 hours.

2. Potent And Sustained Acid Control

Aciloc gives steady acid control over 8 to 12 hours.

• Nighttime Relief: It really works well at stopping acid from coming up at night. This means you are less likely to wake up with heartburn or a sour taste.
• Healing Rates: Studies have found that Aciloc helps heal acid damage in the oesophagus better than usual treatments. Aciloc heals effectively.

3. Dosing Flexibility

You can take this medicine at any time of the day, before or even after having your food, unlike other medicines.

Dosage Details Of Aciloc 300 Mg:

✓ Dosage Guidelines:

Even though most doctors recommend taking a single pill each time, the doctors will check and assess the type of condition, its severity and match the dosage based on your age and health.

• For GERD/Reflux: A single pill of 150 mg for mild and 300 mg for severe issues taken for at least 8 weeks.
• For Gastric/Duodenal Ulcers: A single pill for 4 to 6 months.

✓ Missed Dose:

Take the medicine if you remember about your missed dose within 10 hours of the next dose, or else skip it. However, do not double up your dose the next time if you forget taking the previous dose.

✓ Overdose:

Some overdose studies show that patients can have a few issues within minutes, like stomach pain, diarrhea, nausea, or dizziness.

Drug Interactions Of Aciloc 300 Mg:

1. Absorption Interactions (Ph-Dependent)

Aciloc reduces stomach acids, and thus any other medicine needing low pH activation may be suppressed. Here are a few types of medicines that may not work with Aciloc-

• Antifungals: Ketoconazole, Itraconazole.
• Cancer Medications: pills like Erlotinib or Gefitinib.
• HIV Medications: Atazanavir, Nelfinavir.

2. Liver Enzyme Interactions (Cyp450 System)

• CYP3A4 Inhibitors: Avoid a pill like Clarithromycin, which can inhibit the CYP3A4, causing drug toxicity.
• CYP3A4 Inducers: pills like Rifampin for TB can actually increase the metabolism of Ranitidine, thus reducing its effects.
• Digoxin: Aciloc can slow down the action of Digoxin, causing drug toxicity.

Side Effects Of Aciloc 300 Mg:

✓ Common Side Effects

• Diarrhea: Take more water,r but with persistent diarrhea, you need a reduction of the daily dose. Nausea: Take the medicine only after a light meal and keep drinking water.
• Mild stomach pain: take water and see if it persists for a few days, along with some soft bloating, in which case, you need a checkup with the doctors.
• Taste changes: keep taking water to avoid buildup of a sour or metallic taste in the mouth.
• Headache or dizziness: Avoid taking the medicine right after night’s sleep or on an empty stomach.

✓ Rare But Serious Side Effects

• Liver Enzymes: Immediately talk with the doctor and consult with the dose for a reduction in liver enzymes.
• Persistent Stomach cramps: Doctors can tell you to stop using the medicine for a few days.
• Yellowing of the eyes or skin, dark urine: All these are signs of jaundice; talk with your doctors immediately.

Precautions And Warnings Of Aciloc 300 Mg:

✓ Allergic problems:

Avoid taking the medicine if you are allergic to Ranitidine with an earlier experience or any of its other excipients in the drug. If you mistakenly use it in such cases, it can result in-

Skin rashes or hives

Swelling of the lips and mouth

Inflammation of the limbs

Severe Liver or Kidney Impairment

✓ Liver or kidney disorders:

A patient with any kind of existing liver or kidney condition should tell it to the doctors about it. You will have to go through LFT, KFT, creatinine, bilirubin, and other tests.

✓ Pregnancy & Breastfeeding:

During pregnancy, this medicine is given to control signs of GERD or gastric ulcers, but in limited amounts. However, in the case of breastfeeding, it is not safe at all as it passes on to your breastmilk.

Safety Advice

✓ Long-Term Use Considerations

It can alter stomach acid production and secretion if taken daily for more than a year.

It is generally not safe for use in children below the age of 6 years.

✓ With Existing Health Conditions:

• Inform the doctors if you have existing health conditions such as-
• Recent fractures
• Other stomach infections caused by fungi or worms
• Stomach or intestinal cancer, where the patient is undergoing chemotherapy
• In such cases, the doctors adjust the dose and keep you under regular checkup.

✓ Regular Health Checkup And Tests:

Doctors will conduct regular tests, success-

• LFT
• Creatinine
• CBC count
• Saliva test

✓ Alcohol:

Alcohol use can irritate the stomach even further, risking severe stomach pain, severe bloating, and other side effects like nausea or dizziness.

Storage Details:

• Store at room temperature (below 25°C)
• Keep away from heat and direct sunlight
• Protect from light exposure
• Keep in the original packaging/blister pack
• Store in a cool, dry place
• Avoid bathrooms or humid environments

Where To Buy Aciloc 300 Mg In Australia?

You can rely on trusted platforms such as australiarxmeds.com for secure and discreet delivery across Australia.

Aciloc 300 mg is available for online purchase through pharmacy websites, but it’s important to choose reputable and licensed sellers to guarantee product quality, authenticity, and safety.

Summary